Active X Clinics

How Pain Works: The 6 simple variables in the Pain Equation

Can Pain Be Explained with an Equation?

Doctors and researchers have written a lot about how pain works, but it’s often hard to understand. In 2020, the International Association for the Study of Pain (IASP) updated its definition of pain:

“An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage.”

This means pain is not just about injury. It’s also shaped by your emotions, thoughts, and life experiences.

I’ve worked with people who have persistent pain for over 30 years. Helping people understand how pain works is a big part of helping them feel better.

This became clear to me after a wasp sting.


The Wasp That Taught Me About Pain

One morning, I was cycling to work when I felt a sharp sting on my leg. I looked down and saw a wasp. Instead of panicking, I paid close attention to what was happening.

For the next 45 minutes, my pain went up and down. Sometimes it really hurt. Other times, I didn’t notice it at all.

That ride gave me a big idea. In order to explain how pain works, I came up with an equation to explain pain:

P = (N – MWP) + (NO – PO) + ATBP + PVOP

Let’s break it down.


How Pain Works: The Pain Equation Explained

P = Pain

This is the pain you feel right now.

N = Nociception

This means your body has sensed something harmful, like an injury or heat. But sensing harm doesn’t always mean pain. Your brain decides whether it hurts or not.

MWP = Movement Without Pain

Moving in a way that doesn’t hurt can help reduce pain. When you move, your body sends signals that block pain. Exercise also releases chemicals that make you feel better.

NO = Negative Outlook

When you’re stressed, scared, or feeling low, pain can feel worse. These emotions activate the same brain areas as pain. This is a huge part of how pain works.

PO = Positive Outlook

When you feel happy, safe, or connected to others, pain often feels less intense. Fun activities help your brain fight pain.

ATBP = Attention to Body Part

The more you think about the pain, the more you feel it. If you’re distracted, pain often fades. That’s why pain can feel worse at night when you’re not busy.

PVOP = Previous Volume of Pain

If you’ve had a lot of pain before, your body may become more sensitive to it. Your brain and nerves learn pain—this is called “central sensitisation.”


What If My Pain Is Worse?

You might think, “My pain is much worse than a wasp sting.” And you’re probably right.

But this equation still helps. For example, shark attack survivors often don’t feel pain at first. And some people feel strong pain even without any injury.

Pain is about how your brain sees the situation—not just the damage.


Use the Equation to Help Yourself

Write this down:

P = (N – MWP) + (NO – PO) + ATBP + PVOP

Now ask yourself:

  • Can I move more without pain?
  • Can I find ways to reduce stress or feel more positive?
  • Can I distract myself from focusing on the pain?

Even small changes in these areas can help reduce pain.


Final Thoughts about how pain works

Pain is real, but it doesn’t always match the amount of damage. Your brain plays a big role in how pain works.

If you understand this, you can take back control. Try things that boost your mood, get you moving, and keep your mind busy.

I hope this helps you understand your pain—and feel better.

If you have ideas about this pain equation, I’d love to hear them.

Stay active and stay hopeful,

Gavin Routledge

Registered osteopath

About the author

Clinic Director at Active X Backs, in Edinburgh, Scotland.  (https://active-x.co.uk/). Co-author of “The Back Book” in 1997 with Gavin Hastings OBE, and author of “Active X Backs; an effective long-term solution to lower back pain” in 2017. Gavin graduated as a Gold Medalist (awarded for Conspicuous Merit) in 1991 from the British School of Osteopathy. He was Vice Patron of the British School of Osteopathy from 2005-2015, and a Director of the British Society of Lifestyle Medicine 2018-19. He has an MSc in The Clinical Management of Pain from the University of Edinburgh, and runs regular free webinars for those affected by lower back pain and sciatica.

  1.  Merskey H, Albe Fessard D, Bonica JJ, Carmon A, Dubner R, Kerr FWL, Lindblom U, Mumford JM, Nathan PW, Noordenbos W, Pagni CA, Renaer MJ, Sternbach RA, Sunderland S. Pain terms: a list with definitions and notes on usage. Recommended by the IASP subcommittee on taxonomy. PAIN 1979;6:pp249–52.
  2.  International Association for the Study of Pain (2019) IASP’s Proposed New Definition of Pain Released for Comment. Available at: https://www.iasp-pain.org/PublicationsNews/NewsDetail.aspx?ItemNumber=9218 (accessed 25 May 2020).
  3. Melzack, P.D. Wall PD. Pain mechanisms: a new theory. Science. 1965 [archived 2012-01-14];150(3699): pp 971–9
  4. Arntz, L. Dreessen, H. Merckelbach.  Attention, not anxiety, influences pain. Behav Res Ther. 1991;29(1):pp41‐50
  5. G. L. Moseley, D. S. Butler  Fifteen Years of Explaining Pain: The Past, Present, and Future. The Journal of Pain. September 2015
  6. Jackson, Y Wang, H Fan Associations Between Pain Appraisals and Pain Outcomes:Meta-Analyses of Laboratory Pain and Chronic Pain Literatures. The Journal of Pain, Vol 15, No 6 (June), 2014: pp 586-601